Purple drank is a recreational drug which includes a prescription-strength cough syrup used in a manner inconsistent with its labeling and mixed with a carbonated soft drink. Promethazine is used to relieve the symptoms of allergic reactions such as allergic rhinitis (runny nose and watery eyes caused by allergy to pollen, mold or dust), allergic conjunctivitis (red, watery eyes caused by allergies), allergic skin reactions, and allergic reactions to blood or plasma products. Promethazine and Codeine - Clinical Pharmacology Mechanism of Action. Codeine. Codeine is an opioid agonist relatively selective for the mu-opioid receptor, but with a much weaker affinity than morphine. Re: Green Promethazine.is codeine in it? Promethazine is an antihistamine and is often prescribed as such. It is sometimes taken with opiates (including codeine) to potentiate their effect, as well as reduce nausea and itching. PRINCIPAL DISPLAY PANEL mL Bottle Label. WOCKHARDT. NDC 60432-606-16. PROMETHAZINE WITH CODEINE COUGH SYRUP (Promethazine Hydrochloride 6.25 mg/5mL & Codeine Phosphate 10 mg/5 mL) CV Codeine is a narcotic. It is a pain reliever and a cough suppressant. Promethazine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. Codeine is used to relieve mild to moderate pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine will help relieve symptoms but will not treat the cause of symptoms or speed recovery. La prométhazine est un neuroleptique antihistaminique inhibiteur des récepteurs H1 de la famille des phénothiazines. C'est un médicament utilisé dans le traitement de l'allergie et de l'insomnie passagère. Easy-to-read patient leaflet for Promethazine and Codeine. Includes indications, proper use, special instructions, precautions, and possible side effects. The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients less than 6 years of age. Concomitant administration of promethazine products with other respiratory depressants has an association with respiratory depression, and sometimes death, in.